Domperidone
Domperidone (R33812, Motilium) is a selective dopamine D2 and D3 receptor antagonist. Its primary action in the chemoreceptor trigger zone (area postrema) makes it a valuable research tool for studying the mechanisms and treatment of nausea and vomiting in both in vitro and in vivo models.
Product Specifications
CAS Number
57808-66-9
Product Name Alternative
D2, D3, Dopamine Receptor, DopamineReceptor, dopamine, Dopamine, Domperidone, blood-brain barrier, antiemetic, adverse, inhibit, oral, neurological, nausea, Inhibitor, vomit, R33812, R-33812, R 33812, symptoms, prokinetic
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.39 mM) ; DMSO:103 mg/mL (241.84 mM)
Smiles
ClC1=CC2=C (C=C1) N (C1CCN (CCCN3C (=O) NC4=CC=CC=C34) CC1) C (=O) N2
Molecular Formula
C22H24ClN5O2
Molecular Weight
425.91
Storage Conditions
-20°C
Notes
For research use only.
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