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Sorafenib tosylate

Sorafenib tosylate is a multikinase inhibitor with potent activity against targets including Raf-1, VEGFR-3, and B-Raf (IC50s: 6, 20, 22 nM, respectively) . It is widely used in preclinical research for investigating oncogenic signaling pathways and has demonstrated antitumor effects in both cellular assays and animal models of various cancers.

Product Specifications

CAS Number

475207-59-1

Product Name Alternative

BAY 43-9006

Field of Research

Cell Biology

Purity

99.20% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:200 mg/mL (313.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.85 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cc1ccc (cc1) S (O) (=O) =O.CNC (=O) c1cc (Oc2ccc (NC (=O) Nc3ccc (Cl) c (c3) C (F) (F) F) cc2) ccn1

Molecular Formula

C21H16ClF3N4O3·C7H8O3S

Molecular Weight

637.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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