Sorafenib
Sorafenib is an orally active multikinase inhibitor targeting Raf, VEGFR, PDGFRβ, and others, with IC50 values in the nanomolar range. It exhibits antitumor activity by inducing apoptosis, autophagy, and ferroptosis, making it a valuable tool for cancer research in both cellular and animal models.
Product Specifications
CAS Number
284461-73-0
Product Name Alternative
BAY 43-9006
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Raf-1 inhibitor (and other kinases)
Form
Powder
Solubility
Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml) .
Smiles
O (C=1C=C (C (NC) =O) N=CC1) C2=CC=C (NC (NC3=CC (C (F) (F) F) =C (Cl) C=C3) =O) C=C2
Molecular Formula
C21H16ClF3N4O3
Molecular Weight
464.83
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4- (4- (3- (4-chloro-3- (trifluoromethyl) phenyl) ureido) phenoxy) -N-methylpicolinamide
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
