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Voriconazole

Voriconazole (UK-109496) is a triazole antifungal compound that acts as a potent inhibitor of fungal sterol 14-alpha-demethylase and the mammalian cytochrome P-450 CYP3A enzyme. It is widely used in research for studying antifungal mechanisms, drug interactions, and in both in vitro susceptibility testing and in vivo infection models.

Product Specifications

CAS Number

137234-62-9

Product Name Alternative

14-α Demethylase, blastomycosis, broad-spectrum, antifungal, murine, inhibit, Inhibitor, Fungal, pulmonary, UK 109496, UK109496, UK-109496, Voriconazole, triazole

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.31 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:247 mg/mL (707.11 mM) ; Ethanol:16 mg/mL (45.8 mM)

Smiles

CC (C1=NC=NC=C1F) C (O) (CN1C=NC=N1) C1=CC=C (F) C=C1F

Molecular Formula

C16H14F3N5O

Molecular Weight

349.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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