Voriconazole
Voriconazole (UK-109496) is a triazole antifungal compound that acts as a potent inhibitor of fungal sterol 14-alpha-demethylase and the mammalian cytochrome P-450 CYP3A enzyme. It is widely used in research for studying antifungal mechanisms, drug interactions, and in both in vitro susceptibility testing and in vivo infection models.
Product Specifications
CAS Number
137234-62-9
Product Name Alternative
14-α Demethylase, blastomycosis, broad-spectrum, antifungal, murine, inhibit, Inhibitor, Fungal, pulmonary, UK 109496, UK109496, UK-109496, Voriconazole, triazole
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.31 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:247 mg/mL (707.11 mM) ; Ethanol:16 mg/mL (45.8 mM)
Smiles
CC (C1=NC=NC=C1F) C (O) (CN1C=NC=N1) C1=CC=C (F) C=C1F
Molecular Formula
C16H14F3N5O
Molecular Weight
349.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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