Mitoxantrone dihydrochloride
Mitoxantrone dihydrochloride is an anthracenedione-based chemotherapeutic agent that functions as a type II topoisomerase inhibitor. It is widely used in cancer research, including in vitro cytotoxicity assays and in vivo models for studying leukemia, lymphoma, and breast cancer.
Product Specifications
CAS Number
70476-82-3
Product Name Alternative
Topoisomerase, Topo II, Protein kinase C, PKC, HL60 cells, MCF-7, leukaemia, Endogenous Metabolite, Inhibitor, inhibit, NSC 301739, Orthopoxvirus, lymphocytes, NSC301739, NSC-301739, Mitoxantrone, Mitoxantrone 2HCl, Mitoxantrone dihydrochloride, Mitoxantrone Dihydrochloride, Mitoxantrone Hydrochloride, Mitoxantrone hydrochloride, mitozantrone, Mitozantrone, mitozantrone dihydrochloride, mitozantrone Dihydrochloride, breast cancer, antitumor, Apoptosis, B-CLL cells
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.05% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.87 mM) ; DMSO:38.8 mg/mL (74.99 mM) ; H2O:2.6 mg/mL (5.03 mM)
Smiles
Cl.OCCNCCNc1c2C (=O) c3c (O) ccc (O) c3C (=O) c2c (NCCNCCO) cc1.Cl
Molecular Formula
C22H30Cl2N4O6
Molecular Weight
517.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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