Pancuronium dibromide
Pancuronium bromide is a potent competitive nicotinic acetylcholine receptor antagonist (IC50 = 5.5 nM) used as a neuromuscular blocking agent. It is widely applied in physiological research for skeletal muscle relaxation in vivo and for studying neuromuscular transmission mechanisms in vitro.
Product Specifications
CAS Number
15500-66-0
Product Name Alternative
AChR, Nicotinic acetylcholine receptors, neuromuscular, nAChR, mAChR, Pancuronium, Pancuronium bromide, Pancuronium Bromide, Pancuronium Dibromide, Pancuronium dibromide, Pavulon, inhibit, noradrenaline, Inhibitor, sympathomimetic, Steroid, skeletal, relaxant
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.27% (May vary between batches)
Solubility
DMSO:60 mg/mL (81.89 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.73 mM) ; H2O:136.49 mM
Smiles
[Br-].[Br-].[H][C@@]12C[C@@H] ([C@H] (OC (C) =O) [C@@]1 (C) CC[C@@]1 ([H]) [C@@]2 ([H]) CC[C@@]2 ([H]) C[C@H] (OC (C) =O) [C@H] (C[C@]12C) [N+]1 (C) CCCCC1) [N+]1 (C) CCCCC1
Molecular Formula
C35H60Br2N2O4
Molecular Weight
732.67
Storage Conditions
-20°C
Notes
For research use only.