Saxagliptin hydrate
Saxagliptin hydrate, also known as Onglyza hydrate, is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 of 26 nM and a Ki of 1.3 nM. This compound is widely used in diabetes research to study DPP-4's role in glucose metabolism, employing both in vitro enzymatic assays and in vivo models of type 2 diabetes.
Product Specifications
CAS Number
945667-22-1
Product Name Alternative
Onglyza hydrate, Onglyza Hydrate, p-AKT, inhibit, glucagon-like, glucagon, Inhibitor, insulin, DPP, DPP4, DPP-4, Dipeptidyl Peptidase, diabetes, c-myc, BMS477118 Hydrate, BMS-477118 Hydrate, BMS-477118 hydrate, BMS477118, BMS-477118, BMS 477118 Hydrate, BMS 477118, Saxagliptin hydrate, Saxagliptin Hydrate, Saxagliptin, proliferation, peptide-1, β-catenin
Field of Research
Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.52% (May vary between batches)
Solubility
H2O:1 mg/mL (3 mM) ; DMSO:70 mg/mL (209.94 mM) ; Ethanol:61 mg/mL (182.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6 mM)
Smiles
O.N[C@H] (C (=O) N1[C@H]2C[C@H]2C[C@H]1C#N) C12CC3CC (CC (O) (C3) C1) C2
Molecular Formula
C18H25N3O2·H2O
Molecular Weight
333.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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