Amorolfine hydrochloride
Amorolfine HCl is a morpholine antifungal agent that inhibits ergosterol synthesis by targeting Δ14 reductase and Δ8→Δ7 isomerase, leading to fungal membrane disruption. It is widely used in research for studying antifungal mechanisms and has demonstrated efficacy in both in vitro assays and in vivo models of dermatophyte and yeast infections.
Product Specifications
CAS Number
78613-38-4
Product Name Alternative
Ro 14-4767/002, vaginal candidiasis, Antibiotic, Amorolfine, Amorolfine HCl, anti-fungal, Fungal, onychomycosis
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.05% (May vary between batches)
Solubility
H2O:9 mg/mL (25.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.83 mM) ; Ethanol:66 mg/mL (186.46 mM) ; DMSO:16.67 mg/mL (47.09 mM)
Smiles
Cl.CCC (C) (C) c1ccc (CC (C) CN2C[C@H] (C) O[C@H] (C) C2) cc1
Molecular Formula
C21H36ClNO
Molecular Weight
353.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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