Vinorelbine
Vinorelbine is a semisynthetic vinca alkaloid that acts as a microtubule-targeting agent by binding to tubulin and inhibiting mitotic spindle assembly, leading to metaphase arrest. It is widely used in cancer research, including in vitro cytotoxicity assays and in vivo studies of solid tumor models such as non-small cell lung and breast cancer.
Product Specifications
CAS Number
71486-22-1
Product Name Alternative
MicrotubuleAssociated, Microtubule Associated, KW-2307 base, Tubulin β chain, Vinorelbine
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.62% (May vary between batches)
Solubility
H2O:10 mg/mL (12.84 mM) ; DMSO:100 mg/mL (128.38 mM)
Smiles
C (C) [C@@]12[C@]3 ([C@@]4 ([C@] ([C@] (C (OC) =O) (O) [C@@H]1OC (C) =O) (N (C) C=5C4=CC (=C (OC) C5) [C@]6 (C (OC) =O) C7=C (C=8C (N7) =CC=CC8) C[N@@]9C[C@] (C6) (C=C (CC) C9) [H]) [H]) CCN3CC=C2) [H]
Molecular Formula
C45H54N4O8
Molecular Weight
778.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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