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Pioglitazone

Pioglitazone is a potent and selective PPARγ agonist with EC50 values of 0.93 μM (human) and 0.99 μM (mouse) . This orally active small molecule is widely used in diabetes research for in vitro mechanistic studies and in vivo models of insulin resistance and glucose homeostasis.

Product Specifications

CAS Number

111025-46-8

Product Name Alternative

Pioglitazone, PPARγ, PPAR, Peroxisome proliferator-activated receptors, U72107, U-72107, U 72107, inhibit, ligand-binding, Ferroptosis, Inhibitor, diabete, domain, blood glucose

Field of Research

Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Purity

95.00% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2 mg/mL (5.61 mM) ; DMSO:28.8 mg/mL (80.8 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

C (C1C (=O) NC (=O) S1) C2=CC=C (OCCC3=CC=C (CC) C=N3) C=C2

Molecular Formula

C19H20N2O3S

Molecular Weight

356.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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