Pioglitazone
Pioglitazone is a potent and selective PPARγ agonist with EC50 values of 0.93 μM (human) and 0.99 μM (mouse) . This orally active small molecule is widely used in diabetes research for in vitro mechanistic studies and in vivo models of insulin resistance and glucose homeostasis.
Product Specifications
CAS Number
111025-46-8
Product Name Alternative
Pioglitazone, PPARγ, PPAR, Peroxisome proliferator-activated receptors, U72107, U-72107, U 72107, inhibit, ligand-binding, Ferroptosis, Inhibitor, diabete, domain, blood glucose
Field of Research
Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
95.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (5.61 mM) ; DMSO:28.8 mg/mL (80.8 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C (C1C (=O) NC (=O) S1) C2=CC=C (OCCC3=CC=C (CC) C=N3) C=C2
Molecular Formula
C19H20N2O3S
Molecular Weight
356.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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