Losartan
Losartan, also known as DuP-753, is a selective antagonist of the angiotensin II type 1 (AT1) receptor. It is widely used in research to study the renin-angiotensin system in models of hypertension, cardiovascular disease, and renal function, both in vitro and in vivo.
Product Specifications
CAS Number
114798-26-4
Product Name Alternative
Angiotensin Receptor, AT1 receptor, DuP 753, DuP753, DuP-753, inhibit, Losartan, Inhibitor
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.80% (May vary between batches)
Solubility
DMSO:125 mg/mL (295.57 mM) ; Saline:33.3 mg/mL (78.74 mM)
Smiles
CCCCC1=NC (Cl) =C (CO) N1CC1=CC=C (C=C1) C1=CC=CC=C1C1=NNN=N1
Molecular Formula
C22H23ClN6O
Molecular Weight
422.91
Storage Conditions
-20°C
Notes
For research use only.
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