Sitagliptin
Sitagliptin is a selective DPP-4 inhibitor used in type 2 diabetes research. By blocking DPP-4, it increases active incretin levels, enhancing insulin secretion and suppressing glucagon. This mechanism is widely studied in both in vitro enzymatic assays and in vivo models of metabolic disease.
Product Specifications
CAS Number
486460-32-6
Product Name Alternative
Dipeptidyl Peptidase, DPP, DPP4, DPP-4, Autophagy, Inhibitor, inhibit, MK 0431, MK0431, MK-0431, Sitagliptin
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
DMSO:170 mg/mL (417.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.91 mM) ; H2O:< 1 mg/mL (insoluble)
Smiles
N[C@@H] (CC (=O) N1CCn2c (C1) nnc2C (F) (F) F) Cc1cc (F) c (F) cc1F
Molecular Formula
C16H15F6N5O
Molecular Weight
407.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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