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Acarbose

Acarbose (BAY g 5421) is a potent alpha-glucosidase inhibitor (IC50=11 nM) used as a hypoglycemic agent in research. It is applied in studies of type 2 diabetes, both in vitro for enzyme kinetics and in vivo to investigate its synergistic effects with insulin or sulfonylureas on postprandial glucose control.

Product Specifications

CAS Number

56180-94-0

Product Name Alternative

BAY g 5421, BAY g5421, BAY g-5421, antihyperglycemic, anti-diabetes, Acarbose, oral, inhibit, mellitus, Inhibitor, insulin, Glucosidase, α-glucosidase

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

H2O:64.5 mg/mL (99.91 mM) ; DMSO:50 mg/mL (77.45 mM)

Smiles

O ([C@@H]1[C@@H] (CO) O[C@H] (O[C@@H] ([C@@H] ([C@H] (C=O) O) O) [C@@H] (CO) O) [C@H] (O) [C@H]1O) [C@@H]2[C@H] (O) [C@@H] (O) [C@H] (N[C@H]3C=C (CO) [C@@H] (O) [C@H] (O) [C@H]3O) [C@@H] (C) O2

Molecular Formula

C25H43NO18

Molecular Weight

645.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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