Metyrapone
Metyrapone (NSC-25265) is a potent and selective inhibitor of steroid 11β-hydroxylase, the enzyme encoded by CYP11B1. It is widely used in both clinical diagnostics for assessing hypothalamic-pituitary-adrenal axis function in Cushing's syndrome and in biomedical research to modulate corticosteroid levels in vitro and in vivo.
Product Specifications
CAS Number
54-36-4
Product Name Alternative
Cytochrome P450, CYPs, Cushing's syndrome, depression, Autophagy, behavior, Camphor 5-monooxygenase, aldosterone, 11β-hydroxylase, 11β-HSD1, inhibit, NSC 25265, NSC25265, NSC-25265, Metyrapone, Inhibitor, Endogenous Metabolite, emotion, water maze, Sprague-Dawley rats, Su4885, Su-4885, Su 4885
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
Cytochrome P450 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
CC (C) (C (=O) c1cccnc1) c1cccnc1
Molecular Formula
C14H14N2O
Molecular Weight
226.27
Storage Conditions
RT
Notes
For research use only.
Other Product Names
2-Methyl-1,2-dipyridin-3-yl-propan-1-one
Available Sizes
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