Digitoxin
Digitoxin is a potent Na+/K+-ATPase inhibitor with an EC50 of 0.78 μM. This cardenolide is widely used in cardiovascular research to study ion transport mechanisms and has been employed in both in vitro assays and in vivo models of heart failure.
Product Specifications
CAS Number
71-63-6
Product Name Alternative
Digitoxin, Digitoxinum, Digitoxoside, inhibit, Na+/K+ ATPase, Na+/K+-ATPase, organic anion transporter, Inhibitor, Unidigin, Sodium potassium pump
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.23% (May vary between batches)
Solubility
DMSO:100 mg/mL (130.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.23 mM)
Smiles
C[C@H]1O[C@H] (C[C@H] (O) [C@@H]1O) O[C@H]1[C@@H] (O) C[C@H] (O[C@H]2[C@@H] (O) C[C@H] (O[C@H]3CC[C@@]4 (C) [C@H] (CC[C@@H]5[C@@H]4CC[C@]4 (C) [C@H] (CC[C@]54O) C4=CC (=O) OC4) C3) O[C@@H]2C) O[C@@H]1C
Molecular Formula
C41H64O13
Molecular Weight
764.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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