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Digitoxin

Digitoxin is a potent Na+/K+-ATPase inhibitor with an EC50 of 0.78 μM. This cardenolide is widely used in cardiovascular research to study ion transport mechanisms and has been employed in both in vitro assays and in vivo models of heart failure.

Product Specifications

CAS Number

71-63-6

Product Name Alternative

Digitoxin, Digitoxinum, Digitoxoside, inhibit, Na+/K+ ATPase, Na+/K+-ATPase, organic anion transporter, Inhibitor, Unidigin, Sodium potassium pump

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

98.23% (May vary between batches)

Solubility

DMSO:100 mg/mL (130.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.23 mM)

Smiles

C[C@H]1O[C@H] (C[C@H] (O) [C@@H]1O) O[C@H]1[C@@H] (O) C[C@H] (O[C@H]2[C@@H] (O) C[C@H] (O[C@H]3CC[C@@]4 (C) [C@H] (CC[C@@H]5[C@@H]4CC[C@]4 (C) [C@H] (CC[C@]54O) C4=CC (=O) OC4) C3) O[C@@H]2C) O[C@@H]1C

Molecular Formula

C41H64O13

Molecular Weight

764.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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