Methylthiouracil
Methylthiouracil is a thiourea-based antithyroid compound that suppresses thyroid hormone synthesis. It is widely used in research to model hyperthyroidism and hyperlipidemia, and its anti-inflammatory properties, including inhibition of TNF-α, IL-6, NF-κB, and ERK1/2, make it applicable for studying related inflammatory pathways in vitro and in vivo.
Product Specifications
CAS Number
56-04-2
Product Name Alternative
Antithyroid, Inhibitor, Interleukin Related, Interleukin, ERK, Extracellular signal regulated kinases, Methylthiouracil, NFkB, NF-kB, NFκB, NF-κB, NSC9378, NSC-9378, Nuclear factor-κB, Nuclear factor-kappaB, inhibit, MTU, NSC 9378, NSC 193526, NSC193526, NSC-193526, Tumor Necrosis Factor Receptor, TNFR, TNF Receptor
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.82% (May vary between batches)
Solubility
DMSO:27 mg/mL (189.9 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (14.07 mM)
Smiles
CC1=CC (=O) NC (=S) N1
Molecular Formula
C5H6N2OS
Molecular Weight
142.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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