Colchicine
Colchicine is a potent natural alkaloid that inhibits microtubule polymerization (IC50 = 3 nM) and acts as a competitive glycine receptor antagonist. It is widely used in research for its anti-inflammatory and immunosuppressive properties, applied in studies of gout, rheumatoid arthritis, Alzheimer's disease models, and NLRP3 inflammasome-related pathologies in both cellular and animal studies.
Product Specifications
CAS Number
64-86-8
Product Name Alternative
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Microtubule depolymerizing agent
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml), in Water (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
COC1=C (OC) C (OC) =C2C (CCC (NC (C) =O) C3=CC (=O) C (OC) =CC=C23) =C1
Molecular Formula
C22H25NO6
Molecular Weight
399.45
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(S) -N- (5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl) acetamide
Available Sizes
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