5-Aminosalicylic Acid
5-Aminosalicylic Acid (5-ASA) is a small molecule acting as a specific PPARγ agonist with additional inhibitory effects on PAK1, NF-κB, and osteopontin. This multi-target activity underpins its utility in research on inflammation and cancer, supported by evidence from both in vitro and in vivo experimental models.
Product Specifications
CAS Number
89-57-6
Product Name Alternative
Endogenous Metabolite, COX, 5Aminosalicylic Acid, 5-Aminosalicylic Acid, 5-ASA, 5 Aminosalicylic Acid, ALOX5, PAK, NFkB, NF-kB, NFκB, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, MPO, inhibit, Glutathione Peroxidase, GlutathionePeroxidase, EndogenousMetabolite, Mesalazine, Mesalamine, Inhibitor, p21 activated kinases, PPARγ, PPAR, Peroxisome proliferator-activated receptors
Field of Research
Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.88% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (21.55 mM) ; Ethanol:29 mg/mL (189.37 mM) ; DMSO:80 mg/mL (522.4 mM)
Smiles
NC1=CC (C (O) =O) =C (O) C=C1
Molecular Formula
C7H7NO3
Molecular Weight
153.14
Storage Conditions
-20°C
Notes
For research use only.
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