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Ketoconazole

Ketoconazole (R-41400) is an imidazole-derived antifungal compound that also acts as a potent CYP3A4 enzyme inhibitor. It is widely used in biochemical research to study drug metabolism, enzyme inhibition, and fungal pathogenesis in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

65277-42-1

Product Name Alternative

12-hydroxylase, 17-hydroxylase, (±) -Ketoconazol, Cyclosporine oxidase, CYP24A1, CYP3A4, CYPs, Cytochrome P450, Extina, Fungal, NADPHoxidase, Ketoconazol, Ketoconazole, Inhibitor, inhibit, Steroid 21-hydroxylase, Ras, Xolegel, R41400, R-41400, R 41400, Testosterone 6 beta-hydroxylase

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

>98%

Bioactivity

Cytochrome P450 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml) .

Smiles

C ([C@]1 (O[C@@H] (COC2=CC=C (C=C2) N3CCN (C (C) =O) CC3) CO1) C4=C (Cl) C=C (Cl) C=C4) N5C=CN=C5

Molecular Formula

C26H28Cl2N4O4

Molecular Weight

531.43

Storage Conditions

RT

Notes

For research use only.

Other Product Names

(±) -1-[4- (4-{[-2- (2,4-Dichlorophenyl) -2- (1H-imidazol-1-ylmethyl) -1,3-dioxolan-4-yl]methoxy}phenyl) piperazin-1-yl]ethan-1-one

Available Sizes

Frequently Asked Questions

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