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Pranlukast

Pranlukast (ONO-1078) is a selective antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), used to inhibit bronchoconstriction in asthma research. It is widely applied in both in vitro binding assays and in vivo models of allergic airway inflammation to study leukotriene-mediated pathways.

Product Specifications

CAS Number

103177-37-3

Product Name Alternative

ONO 1078

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

>98%

Bioactivity

Leukotriene CysLT1 antagonist; GPR17 antagonist

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml)

Smiles

N (C (=O) C1=CC=C (OCCCCC2=CC=CC=C2) C=C1) C3=C4C (C (=O) C=C (O4) C=5NN=NN5) =CC=C3

Molecular Formula

C27H23N5O4

Molecular Weight

481.51

Storage Conditions

RT

Notes

For research use only.

Other Product Names

N-[4-oxo-2- (2H-tetrazol-5-yl) chromen-8-yl]-4- (4-phenylbutoxy) benzamide

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