Pranlukast
Pranlukast (ONO-1078) is a selective antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), used to inhibit bronchoconstriction in asthma research. It is widely applied in both in vitro binding assays and in vivo models of allergic airway inflammation to study leukotriene-mediated pathways.
Product Specifications
CAS Number
103177-37-3
Product Name Alternative
ONO 1078
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
>98%
Bioactivity
Leukotriene CysLT1 antagonist; GPR17 antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
N (C (=O) C1=CC=C (OCCCCC2=CC=CC=C2) C=C1) C3=C4C (C (=O) C=C (O4) C=5NN=NN5) =CC=C3
Molecular Formula
C27H23N5O4
Molecular Weight
481.51
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N-[4-oxo-2- (2H-tetrazol-5-yl) chromen-8-yl]-4- (4-phenylbutoxy) benzamide
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