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Tetrabenazine

Tetrabenazine (Ro 1-9569) is a vesicular monoamine transporter 2 (VMAT2) inhibitor historically used as an antipsychotic and for movement disorders. It serves as a high-affinity research tool for studying vesicular neurotransmitter transport in both in vitro binding assays and in vivo models of hyperkinetic conditions.

Product Specifications

CAS Number

58-46-8

Product Name Alternative

D2, Dopamine Receptor, DopamineReceptor, Aggression, inhibit, MonoamineTransporter, Monoamine Transporter, Inhibitor, Huntington's disease, Synaptic vesicular amine transporter, Tetrabenazine, Ro 1-9569, Xenazine, VMAT2 inhibitor, Tremor

Field of Research

Cell Biology, Neuroscience, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

VMAT2 inhibitor; stem cell - beta cell inducer

Form

Powder

Solubility

Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 9 mg/ml) .

Smiles

O (C) C=1C=C2[C@]3 (N (C[C@H] (CC (C) C) C (=O) C3) CCC2=CC1OC) [H]

Molecular Formula

C19H27NO3

Molecular Weight

317.43

Storage Conditions

RT

Notes

For research use only.

Other Product Names

(3R,11bR) -rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3- (2-methylpropyl) -2H-benzo[a]quinolizin-2-one

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