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Carglumic Acid

Carglumic Acid is an orphan drug approved by the U.S. FDA in 2010 for treating hyperammonemia caused by N-acetylglutamate synthase deficiency. It serves as a replacement activator for carbamoyl phosphate synthetase 1, facilitating ammonia detoxification via the urea cycle, and is utilized in both clinical management and related biochemical research.

Product Specifications

CAS Number

1188-38-1

Product Name Alternative

Carbamino-L-glutamic acid, Carbamoyl-phosphate synthase, Carbamylglutamic acid, Carbaglu, Carglumic Acid, N-Carbamylglutamate, N-Carbamyl-L-glutamic acid, inhibit, Inhibitor, Ureidoglutaric acid

Field of Research

Pharmacology & Drug Discovery

Purity

99.54% (May vary between batches)

Solubility

DMSO:45 mg/mL (236.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.52 mM)

Smiles

[C@@H] (CCC (O) =O) (NC (N) =O) C (O) =O

Molecular Formula

C6H10N2O5

Molecular Weight

190.15

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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