NLRP3-IN-48
NLRP3-IN-48 is an NLRP3 inhibitor. NLRP3-IN-48 targets the NLRP3 protein, affecting the assembly of the NLRP3 inflammasome and thereby inhibiting its activation. NLRP3-IN-48 has anti-inflammatory activity in a mouse model of acute colitis induced by DSS[1].
Product Specifications
UNSPSC
12352211
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-48.html
Smiles
CC/C=C(C)/C(NC1=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2/C=C/[N+]([O-])=O)C=C1)=O
Molecular Formula
C24H26N2O5
Molecular Weight
422.47
References & Citations
[1]Ruan B, et al. Design, Synthesis, in Vitro and in Vivo Biological Evaluation of Pterostilbene Derivatives for the Treatment of Inflammatory Bowel Disease. Chem Biodivers. 2024 Aug 9:e202401081.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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