PF-06424439 methanesulfonate
PF-06424439 methanesulfonate is a potent and selective DGAT2 inhibitor with an IC50 of 14 nM. This orally available, noncompetitive, and slowly reversible inhibitor is used in research to investigate lipid metabolism in both in vitro and in vivo models, particularly for metabolic and liver disease studies.
Product Specifications
CAS Number
1469284-79-4
Product Name Alternative
Mono- acylglycerol acyltransferase, Inhibitor, inhibit, Acyltransferase, acyl-CoA:cholesterol acyltransferase, DGAT2, Diacylglycerol acyltransferase, Diglyceride acyltransferase, PF 06424439, PF 06424439 methanesulfonate, PF06424439, PF-06424439, PF06424439 methanesulfonate, PF-06424439 methanesulfonate
Field of Research
Metabolism Research
Purity
99.77% (May vary between batches)
Solubility
H2O:99 mg/mL (184.68 mM) ; DMSO:262.5 mg/mL (489.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.33 mM)
Smiles
CS (O) (=O) =O.Clc1cnn (c1) C1 (CC1) c1nc2ccc (nc2[nH]1) N1CCC[C@H] (C1) C (=O) N1CCCC1
Molecular Formula
C23H30ClN7O4S
Molecular Weight
536.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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