Brepocitinib P-Tosylate
Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent, dual JAK1 and TYK2 inhibitor with respective IC50 values of 17 nM and 23 nM. It is a research tool for investigating JAK/STAT signaling in immunological and inflammatory diseases, with applications in both in vitro cellular assays and in vivo preclinical models.
Product Specifications
CAS Number
2140301-96-6
Product Name Alternative
Brepocitinib P Tosylate, Brepocitinib PTosylate, Brepocitinib P-Tosylate, inhibit, Janus kinase, JAK3, JAK, JAK1, JAK2, Inhibitor, PF-06700841 P-Tosylate
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.99% (May vary between batches)
Solubility
DMSO:23.33 mg/mL (41.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.56 mM)
Smiles
Cc1ccc (cc1) S (O) (=O) =O.Cn1cc (Nc2nccc (n2) N2CC3CCC (C2) N3C (=O) [C@@H]2CC2 (F) F) cn1
Molecular Formula
C25H29F2N7O4S
Molecular Weight
561.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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