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Brepocitinib P-Tosylate

Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent, dual JAK1 and TYK2 inhibitor with respective IC50 values of 17 nM and 23 nM. It is a research tool for investigating JAK/STAT signaling in immunological and inflammatory diseases, with applications in both in vitro cellular assays and in vivo preclinical models.

Product Specifications

CAS Number

2140301-96-6

Product Name Alternative

Brepocitinib P Tosylate, Brepocitinib PTosylate, Brepocitinib P-Tosylate, inhibit, Janus kinase, JAK3, JAK, JAK1, JAK2, Inhibitor, PF-06700841 P-Tosylate

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.99% (May vary between batches)

Solubility

DMSO:23.33 mg/mL (41.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.56 mM)

Smiles

Cc1ccc (cc1) S (O) (=O) =O.Cn1cc (Nc2nccc (n2) N2CC3CCC (C2) N3C (=O) [C@@H]2CC2 (F) F) cn1

Molecular Formula

C25H29F2N7O4S

Molecular Weight

561.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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