Pifithrin-α, p-Nitro, Cyclic
Pifithrin-α, p-Nitro, Cyclic (PFN-α) is a cell-permeable, active-form inhibitor of the p53 tumor suppressor protein. It is widely used in research to transiently inhibit p53-dependent apoptosis and cell cycle arrest, facilitating studies in neurobiology, oncology, and ischemia-reperfusion injury across both in vitro and in vivo models.
Product Specifications
CAS Number
60477-38-5
Product Name Alternative
Cell, cortical, P53, p53-triggered, neurons, inhibit, Inhibitor, MDM-2/p53, death, expression, Pifithrin α, p Nitro, Cyclic, Pifithrin-a, p-Nitro, Cyclic, Pifithrin-alpha, p-Nitro, Cyclic, Pifithrinα, pNitro, Cyclic, Pifithrin-α, p-Nitro, Cyclic, p21, WAF1, PFN-a, PFN-alpha, PFN-α, posttranscriptional
Field of Research
Cell Biology
Purity
99.43% (May vary between batches)
Solubility
DMF:12.5 mg/mL (41.76 mM) ; DMSO:5 mg/mL (16.7 mM)
Smiles
[O-][N+] (=O) C1=CC=C (C=C1) C1=CN2C (SC3=C2CCCC3) =N1
Molecular Formula
C15H13N3O2S
Molecular Weight
299.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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