Uzansertib phosphate
Uzansertib phosphate (INCB053914 phosphate) is an orally bioavailable, ATP-competitive pan-PIM kinase inhibitor, demonstrating potent activity against PIM1, PIM2, and PIM3. It is a research tool used in vitro and in vivo to study oncology, hematological malignancies, and signaling pathways involving PIM kinases.
Product Specifications
CAS Number
2088852-47-3
Product Name Alternative
Pim, Pim kinases, PIM3, PIM2, PIM1, Uzansertib, Uzansertib Phosphate, Uzansertib phosphate, tumor, lines, inhibit, INCB 053914, INCB 053914 Phosphate, INCB053914 phosphate, INCB053914 Phosphate, INCB-053914 Phosphate, INCB053914, INCB-053914, orally, Inhibitor, hematologic, malignancies, cell, activity, ATP-competitive, anti-proliferative, broad
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.64 mM) ; DMSO:5 mg/mL (8.18 mM)
Smiles
O=C (C1=NC (C2=C (F) C=CC=C2F) =C (F) C=C1) NC3=CN=C4C (CC[C@H]4O) =C3N5C[C@@H] (N) [C@H] (O) [C@@H] (C) C5.O=P (O) (O) O
Molecular Formula
C26H29F3N5O7P
Molecular Weight
611.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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