(+) -KCC2 blocker 1
(+) -KCC2 blocker 1 is a potent and selective small-molecule inhibitor of the potassium-chloride cotransporter 2 (KCC2), exhibiting an IC50 of 0.4 μM. This compound is a valuable research tool for investigating the role of KCC2 in neuronal chloride homeostasis, synaptic inhibition, and related pathophysiology in both cellular and animal models of neurological disorders.
Product Specifications
CAS Number
1228439-71-1
Product Name Alternative
(+) KCC2 blocker 1, (+) -KCC-2 blocker 1, (+) KCC2 blocker 1, KCC2 blocker 1, KCC2, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
98.12% (May vary between batches)
Solubility
DMSO:50 mg/mL (120.34 mM)
Smiles
C (C1 (C (OCC2=CC=CC=C2) =O) N (C (C) =O) CCC1) C3=CC=C (S (C) (=O) =O) C=C3
Molecular Formula
C22H25NO5S
Molecular Weight
415.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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