Polyinosinic-polycytidylic acid sodium
Poly (I:C) sodium salt is a synthetic double-stranded RNA analog that potently activates TLR3 and RIG-I/MDA5 pathways. It is widely used in research to model viral infection and stimulate innate immune responses in both in vitro cell cultures and in vivo animal studies.
Product Specifications
CAS Number
42424-50-0
Product Name Alternative
Apoptosis, Apoptosis, annealing, double-stranded, dsRNA, Inhibitor, MDA5, inhibit, immunotherapy, microenvironment, Polyinosinic polycytidylic acid sodium, Polyinosinicpolycytidylic acid sodium, Polyinosinic-polycytidylic acid sodium, Polyinosinic-polycytidylic acid, Poly (I:C), Poly (I:C) sodium, Toll-like Receptor (TLR), proper, TLR, TLR3, tumor, RNA, RIG-I
Field of Research
Cell Biology, Immunology & Inflammation
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble) ; H2O:90 mg/mL (129.42 mM)
Smiles
[NaH].Nc1ccn ([C@@H]2O[C@H] (COP (O) (O) =O) [C@@H] (O) [C@H]2O) c (=O) n1.O[C@@H]1[C@@H] (COP (O) (O) =O) O[C@H] ([C@@H]1O) n1cnc2c1nc[nH]c2=O
Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x.xNa
Molecular Weight
695.403
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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