Pristinamycin IA
Pristinamycin IA (Mikamycin B) is a cyclic peptidomacrolactone antibiotic and a known substrate for the P-glycoprotein efflux pump. It is used in research to study antibiotic mechanisms, bacterial resistance, and P-gp-mediated multidrug resistance in both in vitro and in vivo models.
Product Specifications
CAS Number
3131-03-1
Product Name Alternative
Antibiotic, Bacterial, inhibit, macrolactone, Mikamycin B, Mikamycin IA, Inhibitor, vinblastine, Pgp, P-glycoprotein, Pristinamycin IA, ribosome
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Purity
97.44% (May vary between batches)
Solubility
DMSO:30 mg/mL (34.6 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (2.88 mM)
Smiles
[H][C@@]12CCCN1C (=O) [C@H] (CC) NC (=O) [C@@H] (NC (=O) c1ncccc1O) [C@H] (C) OC (=O) [C@@] ([H]) (NC (=O) [C@]1 ([H]) CC (=O) CCN1C (=O) [C@H] (Cc1ccc (cc1) N (C) C) N (C) C2=O) c1ccccc1
Molecular Formula
C45H54N8O10
Molecular Weight
866.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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