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Unesbulin

Unesbulin (PTC596) is an orally bioavailable small molecule that selectively inhibits the BMI-1 protein. This compound is utilized in preclinical research, including in vitro cell studies and in vivo models, to investigate pathways involved in oncology and stem cell biology.

Product Specifications

CAS Number

1610964-64-1

Product Name Alternative

AML, APC/CCDC20, Apoptosis, BMI1, BMI-1, integration, Inhibitor, leukemia, leukemic, G2/M, inhibit, murine, p53, Moloney, orally, PTC 596, PTC596, PTC-596, Unesbulin, virus

Field of Research

Cell Biology, Molecular Biology

Purity

98.71% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.38 mM) ; DMSO:3.67 mg/mL (8.73 mM)

Smiles

Cc1nc2ccc (F) cc2n1-c1nc (N) c (F) c (Nc2ccc (cc2) C (F) (F) F) n1

Molecular Formula

C19H13F5N6

Molecular Weight

420.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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