BAY-85-8501
BAY-85-8501 is a selective, reversible, and highly potent inhibitor of Human Neutrophil Elastase (HNE) with an IC50 of 65 pM. This small molecule is used in biomedical research on HNE-related pathologies such as COPD and bronchiectasis, involving both in vitro and in vivo studies.
Product Specifications
CAS Number
1161921-82-9
Product Name Alternative
Elastase, Inhibitor, HNE, inhibit, BAY 85 8501, BAY858501, BAY-85-8501, Serine Protease, SerineProtease
Field of Research
Protein Biochemistry
Purity
98.63% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.54 mM) ; DMSO:200 mg/mL (421.53 mM)
Smiles
CN1[C@@H] (C (C#N) =C (C) N (C1=O) c1cccc (c1) C (F) (F) F) c1ccc (cc1S (C) (=O) =O) C#N
Molecular Formula
C22H17F3N4O3S
Molecular Weight
474.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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