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(R) -CR8

(R) -CR8 is the enantiomerically pure R-isomer of a potent and selective cyclin-dependent kinase (CDK) inhibitor. It is widely used in biochemical and cellular research to study cell cycle progression, transcription, and neuronal apoptosis, with applications demonstrated in both in vitro assays and in vivo model systems.

Product Specifications

CAS Number

294646-77-8

Product Name Alternative

Isomer, lesion, Hippocampus, death, CK1δ/ε, cdk2/cyclin A, CDK2/cyclinE, Cdk1/cyclin B, CDK, CDK9/Cyclin T, Cdk5/p25, CDK7/cyclin H, cell, CR 8, CR8, CR-8, CR8, (R) -Isomer, Apoptosis, caspases, (R) -Isomer, (R) ​ ​CR8, (R) ​​CR8, (R) ​-​CR-8, (R) ?-?CR8

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

98.41% (May vary between batches)

Solubility

DMSO:11 mg/mL (25.49 mM)

Smiles

CC[C@H] (CO) Nc1nc (NCc2ccc (cc2) -c2ccccn2) c2ncn (C (C) C) c2n1

Molecular Formula

C24H29N7O

Molecular Weight

431.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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