Simurosertib
Simurosertib (TAK-931) is a potent, ATP-competitive inhibitor of CDC7 kinase with sub-nanomolar IC50. It is a research tool used in vitro and in vivo to study DNA replication, cell cycle progression, and has been investigated in preclinical cancer models.
Product Specifications
CAS Number
1330782-76-7
Product Name Alternative
Division, cycle, Cyclin dependent kinase, CDK, cell, Cdc7, anti-cancer, ATP-competitive, orally, Inhibitor, inhibit, Simurosertib, TAK931, TAK-931, TAK 931
Field of Research
Cell Biology
Purity
99.82% (May vary between batches)
Solubility
DMSO:47 mg/mL (137.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.86 mM)
Smiles
Cc1n[nH]cc1-c1cc2[nH]c (nc (=O) c2s1) [C@@H]1CC2CCN1CC2
Molecular Formula
C17H19N5OS
Molecular Weight
341.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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