(Rac) -MGV354
(Rac) -MGV354 is the racemic form of MGV354, a potent soluble guanylate cyclase (sGC) activator with EC50 values below 0.5 nM in CHO cells and 5 nM in GTM-3E cells. This compound is a valuable research tool for investigating sGC signaling pathways in cardiovascular and pulmonary disease models, both in vitro and in vivo.
Product Specifications
CAS Number
1852495-86-3
Product Name Alternative
Topical, sGC, pressure, inhibit, intraocular, MGV 354, MGV354, MGV-354, ocular, Inhibitor, Guanylate Cyclase, activator, (Rac) MGV354, (Rac) MGV354, (Rac) -MGV354, (Rac) -MGV-354, drop
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.47 mM) ; DMSO:60 mg/mL (104.22 mM)
Smiles
Cc1c (cnn1-c1cccc (n1) -c1cccc2CCC (Nc3ccc (cc3C) C3CCN (CC3) C (=O) C3CC3) c12) C (O) =O
Molecular Formula
C35H37N5O3
Molecular Weight
575.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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