(Rac) -MGV354
(Rac) -MGV354 is the racemic form of MGV354, a potent soluble guanylate cyclase (sGC) activator with EC50 values below 0.5 nM in CHO cells and 5 nM in GTM-3E cells. This compound is a valuable research tool for investigating sGC signaling pathways in cardiovascular and pulmonary disease models, both in vitro and in vivo.
Product Specifications
CAS Number
1852495-86-3
Product Name Alternative
Topical, sGC, pressure, inhibit, intraocular, MGV 354, MGV354, MGV-354, ocular, Inhibitor, Guanylate Cyclase, activator, (Rac) MGV354, (Rac) MGV354, (Rac) -MGV354, (Rac) -MGV-354, drop
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.47 mM) ; DMSO:60 mg/mL (104.22 mM)
Smiles
Cc1c (cnn1-c1cccc (n1) -c1cccc2CCC (Nc3ccc (cc3C) C3CCN (CC3) C (=O) C3CC3) c12) C (O) =O
Molecular Formula
C35H37N5O3
Molecular Weight
575.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1381666 Inquire
Recombinant Pseudomonas syringae pv. phaseolicola Phosphoenolpyruvate carboxylase (ppc), partial
Sign In for Pricing
View Details 
024516 96 Tests
Cystathionine Gamma Lyase (CSE) BioAssayTM ELISA Kit (Rat)
Sign In for Pricing
View Details MPX2281K Each
Magic™ Membrane Protein Mouse KRoom Temperaturecap3 (Keratinocyte associated protein 3) Expressed in vitro E.coli expression system, Full Length
Sign In for Pricing
View Details