Basimglurant
Basimglurant is a potent, selective, and orally bioavailable negative allosteric modulator of the mGlu5 receptor, exhibiting a Kd of 1.1 nM. It has been utilized in preclinical research for investigating neurological disorders, including depression and anxiety, in both in vitro and in vivo models.
Product Specifications
CAS Number
802906-73-6
Product Name Alternative
Inhibitor, inhibit, Metabotropic glutamate receptors, mGlu5, mGluR5, mGluR, CTEP Derivative, Basimglurant, RG 7090, RG7090, RG-7090
Field of Research
Neuroscience
Purity
98.35% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.14 mM) ; DMSO:60 mg/mL (184.18 mM)
Smiles
Cc1nc (C#Cc2ccnc (Cl) c2) c (C) n1-c1ccc (F) cc1
Molecular Formula
C18H13ClFN3
Molecular Weight
325.77
Storage Conditions
-20°C
Notes
For research use only.
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