ROCK inhibitor-2
ROCK inhibitor-2 is a potent and selective small molecule targeting both ROCK1 and ROCK2 kinases, with respective IC50 values of 17 nM and 2 nM. It is widely used in cardiovascular, neurological, and cancer research, facilitating studies on cytoskeletal dynamics in both cellular and animal models.
Product Specifications
CAS Number
1127308-52-4
Product Name Alternative
Inhibitor, inhibit, Rho-kinase, Rho-associated protein kinase, Rho-associated kinase, ROCK2, ROK, ROCK1, ROCK inhibitor 2, ROCK inhibitor2, ROCK inhibitor-2, ROCK
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.85% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.04 mM) ; DMSO:250 mg/mL (752.11 mM)
Smiles
COc1cccc (c1) [C@@H] (C) NC (=O) c1ccc (cc1) -c1ccncc1
Molecular Formula
C21H20N2O2
Molecular Weight
332.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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