RP 70676
RP 70676 is a potent small molecule inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), exhibiting IC50 values of 25 nM and 44 nM against rat and rabbit enzymes, respectively. This tool compound is used in biochemical and cellular assays to investigate ACAT's role in cholesterol esterification and lipid metabolism, with applications in atherosclerosis and lipid storage disease research.
Product Specifications
CAS Number
136609-26-2
Product Name Alternative
RP 70676, RP70676, RP-70676, Rabbit ACAT, Rat ACAT, inhibit, mono- acylglycerol acyltransferase, Inhibitor, ACAT, Acyltransferase, acyl-CoA:cholesterol acyltransferase, Diacylglycerol acyltransferase, Diglyceride acyltransferase
Field of Research
Metabolism Research
Purity
98.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.6 mM) ; DMSO:125 mg/mL (300.06 mM)
Smiles
Cc1cc (C) n (CCCCCSc2nc (c ([nH]2) -c2ccccc2) -c2ccccc2) n1
Molecular Formula
C25H28N4S
Molecular Weight
416.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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