S55746
S55746 (BLC201) is a potent and selective small molecule BCL-2 inhibitor with a Ki of 1.3 nM and a Kd of 3.9 nM. It is a valuable research tool for studying apoptosis mechanisms and has demonstrated anti-tumor activity in both cellular assays and in vivo models of hematological cancers.
Product Specifications
CAS Number
1448584-12-0
Product Name Alternative
Bcl-2, BCL 201, Bcl-xL, BCL201, BCL-201, Bcl-2 Family, BLC 201, BLC201, BLC-201, inhibit, Inhibitor, S55746, S-55746, S 55746
Field of Research
Cell Biology
Purity
97.14% (May vary between batches)
Solubility
DMSO:44 mg/mL (61.9 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.81 mM)
Smiles
Oc1ccc (cc1) N (C (=O) c1cc (-c2cc3OCOc3cc2C (=O) N2Cc3ccccc3C[C@H]2CN2CCOCC2) n2CCCCc12) c1ccccc1
Molecular Formula
C43H42N4O6
Molecular Weight
710.82
Storage Conditions
-20°C
Notes
For research use only.
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