SBI-477
SBI-477 is a chemical probe that stimulates insulin signaling by inhibiting the transcription factor MondoA. This action coordinately reduces triglyceride synthesis and increases basal glucose uptake in human skeletal myocytes, making it a useful tool for studying metabolism and insulin resistance in vitro.
Product Specifications
CAS Number
781628-99-7
Product Name Alternative
MondoA, inhibit, Inhibitor, SBI 477, SBI477, SBI-477
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
95.08% (May vary between batches)
Solubility
DMSO:45 mg/mL (93.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.14 mM)
Smiles
COc1ccc (cc1) -c1csc (NC (=O) c2ccc (OCC (=O) N3CCOCC3) c (OC) c2) n1
Molecular Formula
C24H25N3O6S
Molecular Weight
483.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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