SIBA
SIBA is a synthetic S-adenosylhomocysteine (SAH) analogue that acts as a broad inhibitor of S-adenosylmethionine-dependent transmethylation. It inhibits enzymes like SAH hydrolase and has demonstrated antiviral activity, reversibly blocking herpes simplex virus type 1 (HSV-1) replication in vitro.
Product Specifications
CAS Number
35899-54-8
Product Name Alternative
Chick embryo fibroblasts, 5'-Isobutylthioadenosine, 5'-Deoxy-5'-isobutylthioadenosine, 3 LL, Analog, cancer, HSV, HSV-1, HEp2, Herpes simplex virus, malaria, NucleosideAntimetabolite, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, Parasite, inhibit, Inhibitor, SIBA, SAH, RMS-J1
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Purity
99.15% (May vary between batches)
Solubility
DMSO:90 mg/mL (265.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.72 mM)
Smiles
CC (C) CSC[C@H]1O[C@H] ([C@H] (O) [C@@H]1O) n1cnc2c (N) ncnc12
Molecular Formula
C14H21N5O3S
Molecular Weight
339.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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