Sigma-1 receptor antagonist 3
This potent and selective Sigma-1 receptor antagonist (Ki = 1.14 nM) exhibits over 1000-fold selectivity versus the Sigma-2 receptor. It also inhibits the hERG channel (IC50 = 1.54 μM) . This compound is a valuable research tool for investigating σ1R function in neuropharmacology and cellular stress models, both in vitro and in vivo.
Product Specifications
CAS Number
1639220-17-9
Product Name Alternative
Potassium Channel, Sigmareceptor, Sigma 1 receptor antagonist 3, Sigma receptor, Sigma1 receptor antagonist 3, Sigma-1 receptor antagonist 3, Sigma Receptor, σ1, σ-1 receptor antagonist 3, Inhibitor, hERG, KcsA, inhibit
Field of Research
Pharmacology & Drug Discovery
Purity
99.95% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1nc (nc (OCCCN2CCCCC2) c1Cl) -c1ccc (F) cc1
Molecular Formula
C19H23ClFN3O
Molecular Weight
363.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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