SLC13A5-IN-1
SLC13A5-IN-1 is a potent and selective small molecule inhibitor of the sodium-citrate cotransporter (SLC13A5), demonstrating an IC50 of 22 nM for citrate uptake in HepG2 cells. This compound is a valuable research tool for investigating hepatic metabolism, neuronal excitability, and the role of citrate transport in models of epilepsy and non-alcoholic fatty liver disease (NAFLD) .
Product Specifications
CAS Number
2227548-95-8
Product Name Alternative
Disease, cardiovascular, Citrate, HepG2/14C-Citrate Uptake Assay, Inhibitor, human HEPG2, hSLC3A5, inhibit, metabolic, Na+ channels, Na channels, SLC13A5, SLC13A5 IN 1, SLC13A5IN1, SLC-13A5-IN-1, SLC13A5-IN-1, SodiumChannel, Sodium Channel, SCD, StearoylCoADesaturase (SCD), Stearoyl-CoA Desaturase, StearoylCoA Desaturase (SCD), StearoylCoADesaturase, recombinant hSLC3A5/14C-Citrate Uptake Assay, Uptake
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.11% (May vary between batches)
Solubility
DMSO:5 mg/mL (10.83 mM)
Smiles
S (=O) (=O) (C1=CC (Cl) =CC (Cl) =C1) N2CCC (C (NCC3=CC=C (Cl) C=C3) =O) CC2
Molecular Formula
C19H19Cl3N2O3S
Molecular Weight
461.79
Storage Conditions
-20°C
Notes
For research use only.
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