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SPD304 dihydrochloride

SPD304 dihydrochloride is a selective small molecule inhibitor of TNF-α, functioning by disrupting the active trimeric form of the cytokine with an IC50 of 22 μM. This compound is a valuable research tool for studying TNF-α signaling in cellular models of inflammation and autoimmune diseases.

Product Specifications

CAS Number

1049741-03-8

Product Name Alternative

TNF-α, SPD 304, SPD 304 Dihydrochloride, SPD304, SPD-304, SPD304 Dihydrochloride, SPD304 dihydrochloride, SPD-304 Dihydrochloride, SPD-304 dihydrochloride, TNFα

Field of Research

Cell Biology

Purity

99.25% (May vary between batches)

Solubility

DMSO:6.21 mg/mL (10.01 mM)

Smiles

O=C1C2=C (OC=C1CN (CCN (CC3=CN (C4=C3C=CC=C4) C5=CC=CC (C (F) (F) F) =C5) C) C) C=C (C) C (C) =C2.Cl.Cl

Molecular Formula

C32H34Cl2F3N3O2

Molecular Weight

620.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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