SPD304 dihydrochloride
SPD304 dihydrochloride is a selective small molecule inhibitor of TNF-α, functioning by disrupting the active trimeric form of the cytokine with an IC50 of 22 μM. This compound is a valuable research tool for studying TNF-α signaling in cellular models of inflammation and autoimmune diseases.
Product Specifications
CAS Number
1049741-03-8
Product Name Alternative
TNF-α, SPD 304, SPD 304 Dihydrochloride, SPD304, SPD-304, SPD304 Dihydrochloride, SPD304 dihydrochloride, SPD-304 Dihydrochloride, SPD-304 dihydrochloride, TNFα
Field of Research
Cell Biology
Purity
99.25% (May vary between batches)
Solubility
DMSO:6.21 mg/mL (10.01 mM)
Smiles
O=C1C2=C (OC=C1CN (CCN (CC3=CN (C4=C3C=CC=C4) C5=CC=CC (C (F) (F) F) =C5) C) C) C=C (C) C (C) =C2.Cl.Cl
Molecular Formula
C32H34Cl2F3N3O2
Molecular Weight
620.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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